AOMF uses bio-units and bio-scaffold materials to build personalized in vitro 3D bio-structure models based on the needs of bionic morphology, the biophysiological of the organism or the cell-specific micro-environment. This system can be used to generated organoid model with complex, but controllable morphology; to generate highly stable and reproducible personalized model, to generate precise bioprinting of high-viscosity bionic materials and to generate fully automated high-throughput organoid modeling and drug screening placements.